Atmospheric Solids Analysis Probe (ASAP®) Mass Spectrometry

For further information see the following publications:

Evalustion of Atmospheric Solids Analysis Probe Mass Spectrometry for the analysis of Coal related Model Compounds, Wang, S.Z.; Fan, X,; Zheng, A.L.; Wang, Y.G.; Dou, Y.Q.; Wei, X.Y.; Zhao, Y.P.; Wang, R.Y.; Zong, Z.M.; Zhao, W., Fuel. 2014, 117, 556-563

Atmospheric Solids Analysis Probe-Ion Mobility Mass Spectrometry of Polyproplene, Barrere, Caroline; Maire, Florian; Afonso, Carlos; Giusti, Pierre, Analytical Chemistry Volume 84 Issue 21 Pages 9349-9354 DOI: 10.1021/ac302109q Published: NOV 2012

A Rapid Qualitative Analysis of Natural Products by Atmospheric Solids Analysis Probe Mass Spctrometry (ASAP-MS), Lindberg, J.; DerMarderosian, A., Planta Media Volume 78 Issue 11 Pages 1262-1262 Published AUG 2012

Measurement of Vapor Pressures and Heats of Sublimation of Dicarboxylic Acid Using Atmospheric Solids Analysis Probe Mass Spectrometry, Brums, Emily A.; Greaves, John; Finlayson-Pitts, Barbara J., Journal of Physical Chemistry A Volume 116 Issue 24 Special Issue SI Pages 5900-5909 DOI: 10.1021/jp210021f Published: JUN 21 2012

Analytical Tools for the Analysis of Carotenoids in Diverse Materials, Rivera, S.M.; Canela-Garayoa, R., Joural of Chromatography A Volume 1224 Pages 1-10 DOI: 10.1016/j.chroma.2011.12.025 Published: FEB 10 2012

Evaluating Atmospheric Pressure Solids Analysis Probe (ASAP) Mass Spectrometry for the Analysis of Low Molecular Weight Synthetic Polymers, Smith, Michael J.P.; Cameron, Neil R.; Mosley, Jackie A., Analyst Volume 137 Issue 19 Pages 4524-4530 DOI: 10.1039/c2an35556f Published 2012

Analysis of Nucleosides Using the Atmospheric-Pressure Solids Analysis Probe for Ionization, Rozenski, Jef, International Journal of Mass Spectrometry Volume 304 Issue 2-3 Special Issue SI Pages 204-208 DOI: 10.1016/j.ijms.2011.01.029 Published JUL 1 2011

Application of the Mason-Schamp Equation and Ion Mobility Mass Spectrometry to Identify Structurally Related Compounds in Crude Oil, Ahmed, Arif; Cho, Yun Ju; No, Myoung-han; Koh, Jaesuk; Tomczyk, Nicholas; Giles, Kevin; Yoo, Jong Shin; Kim, Sanghwan, Analytical Chemistry Volume 83 Issue 1 pages 77-83 DoI: 10.1021/ac101934q Published JAN 1 2011

Rapid Detection and Identification of Impurities in Ten 2-Naphthalenamines Using an Atmospheric Pressure Solids Analysis Probe in Conjunction with Ion Mobility Mass Spectrometry, Pan, Hefeng; Lundin, Goran; European Journal of Mass Spectrometry Volume 17 Issue 3 Pages 217-225 DOI: 10.1255/ejms.1125 Published 2011

An Assessment of Atmospheric-Pressure Solids-Analysis Probes for the Detection of Chemicals in Food, Fussell, Paul A.; Chan, Danny; Sharman, Matthew, Trac-Trends in Analytical Chemistry Volume 29 Issue 11 Pages 1326-1335 DOI: 10.1016/j.trac.2010.08.004 Published DEC 2010

Mass Spectrometry of Polycyclic Tetracarboxylic ('ARN') Acids and Tetramethyl Esters, Sutton, Paul A.; Smith, Benjamin E.; Rowland, Steven J., Rapid Communications in Mass Spectrometry Volume 24 Issue 21 Pages 3195-3204 DOI: 10.1002/rcm.4761 Published NOV 2010

Analysis of Vanilla Flavored Food Products Using the Atmospheric Solids Analysis Probe, Lee P.J., Ruel A.M., Balogh M.P., Young P.B., Food Analysis, 2011, 21, No. 3.

IMS/MS Applied to Direct Ionization Using the Atmospheric Solids Analysis Probe, Ion Mobility Spectrometry-Mass Spectrometry, Theory and Applications, McEwen, C.N.; Major, H.; Green, M.; Giles, K.; Trimpin, S., Ed. Wilkins, C.L. and Trimpin, S., CRC Press, 2011, p 171-187.

Rapid Detection and Identification of Counterfeit of Adulterated Products of Synthetic Phosphodiesterase type-5 Injibitors with an Atmospheric So;id Analysis Probe, Twohig, Marian; Skiilton, St. John; Fujimoto, Gordon; Ellor, Nicholas; Plumb, Robert S., Drug Testing and Analysis Volume 2 Issue 1-2 Pages 45-50 DOI: 10.1002/dta.115 Published JAN-FEB 2010

Atmospheric Solids Analysis Probe Mass Spectrometry: A New Approach for Airnborne Particle Analysis, Burns, E.A.; Perraud, V.; Greaves, J.; Finlayson-Pitts, B.J., Anal. Chem., 2010, 82 (14), pp 5922–5927.

Use of an Atmospheric Solids Analysis Probe (ASAP) for High Throughput Screening of Biological Fluids: Preliminary Applications on Urine and Bile, Twohig, M.; Shockcor, J.P.; Wilson, I.D.; Nicholson, J.K.; Plumb, R.S., J. Proteome Res., 2010, 9 (7), pp 3590–3597

Molecular ions and protonated molecules observed in the atmospheric solids analysis probe analysis of steroids, Ray, A.D; Hammond, J,; Major, H, European Journal of Mass Spectrometry, 2010, 16, 169-174.

Laserspray ionization using an atmospheric solids analysis probe for sample introduction, Zydel F, Trimpin S, McEwen CN, J ,Am Soc Mass Spectrom. 2010, 21, 1889-92.

Combination Atmospheric Pressure Solids Analysis Probe and Desorption Electrospray Ionization Mass Spectrometry Ion Source, Lloyd, J.A.; Harron, A.F; McEwen, C.N., Anal. Chem., 2009, 81 (21), pp 9158–9162.

Atmospheric solids analysis probe: a rapid ionization technique for small molecule drugs, Petucci, C.; Diffendal, J., J Mass Spectrom. 2008 Nov;43(11):1565-8.

MS-The Practical Art: Incipient Technologies: Desorption and Thermal Desorption Techniques, M.P. Balogh, LC/GC, 2007, 25, 1184

Open-Air Ionization Minimizes Sample Prep. C. H. Arnaud, Chemical & Engineering News, Oct. 8, 2007, 13, Volume 85, Number 41.

Analysis of the Inhibition of the Ergosteral Pathway in Fungi Using the Atomospheric Solids Analysis Probe(ASAP) Method. C. McEwen and S. Gutteridge, J. Am. Soc. Mass Spectrom., 2007, 17, 1274-1278.

The Practical Art: Alternatives in the Face of Chemical Diversity, M.P. Balogh, LC/GC, 2007, 25, 368.

Analysis of Solids, Liquids, and Biological Tissues Using Solids Probe Introduction at Atmospheric Pressure on Commercial LC/MS Instruments. C.N. McEwen, R.G. McKay, B.S. Larsen, Anal. Chem., 2005, 77, 7826-7831.

Also see the following links for more information:

IonSense Inc. Website for purchase of ASAP Probe:

Water Corporation website for information on their ASAP Probe.

Application note from Agilent on an ASAP Probe analysis.